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Fire in Hong Kong apartment complex leaves 44 dead and 279 missing

Hundreds of firefighters working to control blaze in city’s northern Tai Po district

Transcript: Defying death — The origins of ageing

Hannah Kuchler speaks to Michael Peel, David Gems and Matt Kaeberlein

Stranger Things’ high-stakes final season is an escapist pleasure

After nearly 10 years on screen, the show begins its farewell as the first part of season 5 arrives on Netflix

Two National Guard troops shot near the White House in Washington

Guardsmen are in critical condition and a suspect is in custody, according to officials

Letter: US army’s reliance on private equity is a national security risk

From Ian Gary, Executive Director, Financial Accountability and Corporate Transparency (FACT) Coalition, Washington, DC, US

Letter: Let’s spend on deterrence now, rather than war later

From Jonathan Shaw, Maj Gen (retd), Winchester, Hampshire, UK

Letter: Argentina’s simplistic fixes from abroad can’t continue

From Marcos Roca, Paris, France

Letter: Why shadow AI in hiring mustn’t become embedded

From Khyati Sundaram, CEO of ethical AI hiring experts, Applied, London WC2, UK

Letter: Hooray Henrietta

From Henrietta Dermot, London W4, UK

Scientists map five phases of brain development

‘I’ve forgotten what stage my brain is at’

Japan needs to end its dangerous debt delusion

The country has to face up to the hard truth that it has maxed out on its fiscal flexibility

FT Crossword: Number 18,224

Campbell’s fires executive who criticised its food in recording

Vice-president of IT department alleged to have told a former employee the company made food for ‘poor people’

FirstFT: At least 36 dead, hundreds missing in Hong Kong apartment complex fire

Also in today’s newsletter, two National Guard troops shot near White House, and Rachel Reeves’ Budget raises UK tax take to all-time high

Megadeals hit new record as Wall Street’s animal spirits roar back

Global transactions of $10bn or more hit 63 as Trump deregulation and fading trade war risks spur M&A blitz

Rachel Reeves’ Budget raises UK tax take to all-time high

Burden to reach 38% of GDP by end of parliament

Beige Book shows US labour market deteriorated in November

Employment declined and half of US districts noted weaker labour demand

‘Spend now, pay later’: Reeves’ Budget delays the fiscal pain

Chancellor now more likely to meet her fiscal rules without further policy changes, OBR says

Painful choices on welfare still lie ahead for Reeves despite tax rises

OBR sounds alarm on special needs and sickness spending

Online gambling operators hit with steep tax rises

High street betting shops and fruit machines spared from tax raid as bingo industry enjoys a cut

Freezing of income tax thresholds to drag millions into higher rates

Experts condemn ‘tax rise by stealth’ for many, including minimum wage earners and pensioners

Threshold for repaying student loans to converge with minimum wage

Surprise move from chancellor means some university graduates in England may have to pay back debts sooner

Energy system operator warns of UK gas shortage risk in 2030s

Report raises questions over government’s energy strategy as North Sea production falls

Rachel Reeves’ case of risky risk aversion

It is depressing that a government with such a huge majority dares do so little to transform economic prospects